E-Selectin rabbit pAb – TO8463
TO8463
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50 µL$148.00
100 µL$248.00
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Overview

Product name: E-Selectin rabbit pAb
Reactivity: Human;Rat;Mouse;
Alternative Names: selectin E
Source: Rabbit
Dilutions: IHC-p: 100-300.WB 1:500-2000, ELISA 1:10000-20000
Immunogen: The antiserum was produced against synthesized peptide derived from the N-terminal region of human SELE. AA range:100-150
Storage: -20C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 66kD
GeneID: 6401
Human Swiss-Prot No: P16581
Cellular localization: Cell membrane ; Single-pass type I membrane protein.
Background: The protein encoded by this gene is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis. [provided by RefSeq, Jul 2008],