| Product name: |
EDEM2 rabbit pAb |
| Reactivity: |
Human;Rat;Mouse; |
| Alternative Names: |
EDEM2; C20orf31; C20orf49; ER degradation-enhancing alpha-mannosidase-like 2 |
| Source: |
Rabbit |
| Dilutions: |
Immunohistochemistry: 1/100 – 1/300. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen: |
Synthesized peptide derived from the C-terminal region of human EDEM2. |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Molecular Weight: |
65kD |
| GeneID: |
55741 |
| Human Swiss-Prot No: |
Q9BV94 |
| Cellular localization: |
Endoplasmic reticulum lumen . |
| Background: |
In the endoplasmic reticulum (ER), misfolded proteins are retrotranslocated to the cytosol and degraded by the proteasome in a process known as ER-associated degradation (ERAD). EDEM2 belongs to a family of proteins involved in ERAD of glycoproteins (Mast et al., 2005 [PubMed 15537790]).[supplied by OMIM, Mar 2008], |
