| Product name: |
eIF2B rabbit pAb |
| Reactivity: |
Human;Mouse |
| Alternative Names: |
EIF2B3; Translation initiation factor eIF-2B subunit gamma; eIF-2B GDP-GTP exchange factor subunit gamma |
| Source: |
Rabbit |
| Dilutions: |
Western Blot: 1/500 – 1/2000. ELISA: 1/5000. Not yet tested in other applications. |
| Immunogen: |
Synthesized peptide derived from eIF2B . at AA range: 240-320 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
50kD |
| GeneID: |
8891 |
| Human Swiss-Prot No: |
Q9NR50 |
| Cellular localization: |
cytoplasm,cytosol,eukaryotic translation initiation factor 2B complex, |
| Background: |
The protein encoded by this gene is one of the subunits of initiation factor eIF2B, which catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. It has also been found to function as a cofactor of hepatitis C virus internal ribosome entry site-mediated translation. Mutations in this gene have been associated with leukodystrophy with vanishing white matter. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009], |
