| Product name: |
EKLF rabbit pAb |
| Reactivity: |
Human;Rat;Mouse; |
| Alternative Names: |
KLF1; EKLF; Krueppel-like factor 1; Erythroid krueppel-like transcription factor; EKLF |
| Source: |
Rabbit |
| Dilutions: |
Western Blot: 1/500 – 1/2000. ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from human KLF1 around the non-acetylation site of Lys274. AA range:231-280 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
38kD |
| GeneID: |
10661 |
| Human Swiss-Prot No: |
Q13351 |
| Cellular localization: |
Nucleus . Colocalizes with SUMO1 in nuclear speckles. . |
| Background: |
This gene encodes a hematopoietic-specific transcription factor that induces high-level expression of adult beta-globin and other erythroid genes. The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss-of-function mutations in this gene result in the dominant In(Lu) blood phenotype. [provided by RefSeq, Oct 2009], |
