| Product name: |
EPAS-1 rabbit pAb |
| Reactivity: |
Human;Mouse;Rat |
| Alternative Names: |
EPAS1; BHLHE73; HIF2A; MOP2; PASD2; Endothelial PAS domain-containing protein 1; EPAS-1; Basic-helix-loop-helix-PAS protein MOP2; Class E basic helix-loop-helix protein 73; bHLHe73;HIF-1-alpha-like factor; HLF; Hypoxia-inducible factor 2-alpha; HIF-2-alpha; HIF2-alpha; Member of PAS protein 2; PAS domain-containing protein 2 |
| Source: |
Rabbit |
| Dilutions: |
IF: 1:50-200 Western Blot: 1/500 – 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen: |
Synthesized peptide derived from human EPAS-1 around the non-acetylation site of K385. |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
96kD |
| GeneID: |
2034 |
| Human Swiss-Prot No: |
Q99814 |
| Cellular localization: |
Nucleus . Nucleus speckle . Colocalizes with HIF3A in the nucleus and speckles. . |
| Background: |
endothelial PAS domain protein 1(EPAS1) Homo sapiens This gene encodes a transcription factor involved in the induction of genes regulated by oxygen, which is induced as oxygen levels fall. The encoded protein contains a basic-helix-loop-helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. Mutations in this gene are associated with erythrocytosis familial type 4. [provided by RefSeq, Nov 2009], |
