| Product name: |
EphA4 rabbit pAb |
| Reactivity: |
Human;Rat;Mouse; |
| Alternative Names: |
Ephrin type-A receptor 4 (EC 2.7.10.1;EPH-like kinase 8;EK8;hEK8;Tyrosine-protein kinase TYRO1;Tyrosine-protein kinase receptor SEK) |
| Source: |
Rabbit |
| Dilutions: |
WB 1:1000-2000 ELISA 1:5000-20000 |
| Immunogen: |
Synthesized peptide derived from human EphA4 AA range: 540-620 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Molecular Weight: |
108kD |
| GeneID: |
2043 |
| Human Swiss-Prot No: |
P54764 |
| Cellular localization: |
Cell membrane ; Single-pass type I membrane protein . Cell projection, axon . Cell projection, dendrite . Cell junction, synapse, postsynaptic density membrane . Early endosome . Cell junction, adherens junction . Clustered upon activation and targeted to early endosome. . |
| Background: |
This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2015], |
