| Product name: |
Epiregulin rabbit pAb |
| Reactivity: |
Human;Mouse;Rat |
| Alternative Names: |
Proepiregulin [Cleaved into: Epiregulin (EPR)] |
| Source: |
Rabbit |
| Dilutions: |
IHC-p 1:50-200, ELISA 1:10000-20000 |
| Immunogen: |
Synthetic peptide from human protein at AA range: 71-120 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| GeneID: |
2069 |
| Human Swiss-Prot No: |
O14944 |
| Cellular localization: |
[Epiregulin]: Secreted, extracellular space .; [Proepiregulin]: Cell membrane ; Single-pass type I membrane protein . |
| Background: |
This gene encodes a secreted peptide hormone and member of the epidermal growth factor (EGF) family of proteins. The encoded protein is a ligand of the epidermal growth factor receptor (EGFR) and the structurally related erb-b2 receptor tyrosine kinase 4 (ERBB4). The encoded protein may be involved in a wide range of biological processes including inflammation, wound healing, oocyte maturation, and cell proliferation. Additionally, the encoded protein may promote the progression of cancers of various human tissues. [provided by RefSeq, Jul 2015], |
