| Product name: |
Frizzled-4 rabbit pAb |
| Reactivity: |
Human;Mouse;Rat |
| Alternative Names: |
FZD4; Frizzled-4; Fz-4; hFz4; FzE4; CD antigen CD344 |
| Source: |
Rabbit |
| Dilutions: |
Immunofluorescence: 1/200 – 1/1000. ELISA: 1/5000. Not yet tested in other applications. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from human FZD4. AA range:131-180 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Molecular Weight: |
60kD |
| GeneID: |
8322 |
| Human Swiss-Prot No: |
Q9ULV1 |
| Cellular localization: |
Cell membrane ; Multi-pass membrane protein . |
| Background: |
frizzled class receptor 4(FZD4) Homo sapiens This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence. [provided by RefSeq, Jul 2008], |
