| Product name: |
GABA A Receptor 2 rabbit pAb |
| Reactivity: |
Human;Rat;Mouse |
| Alternative Names: |
Gamma-aminobutyric acid receptor subunit gamma-2 (GABA(A) receptor subunit gamma-2) |
| Source: |
Rabbit |
| Dilutions: |
WB 1:1000-2000, IHC 1:100-200 |
| Immunogen: |
Synthetic Peptide of GABA A Receptor 2 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
55kD |
| GeneID: |
2566 |
| Human Swiss-Prot No: |
P18507 |
| Cellular localization: |
Cell junction, synapse, postsynaptic cell membrane ; Multi-pass membrane protein . Cell membrane ; Multi-pass membrane protein . Cell projection, dendrite . Cytoplasmic vesicle membrane . |
| Background: |
This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammlian brain, where it acts at GABA-A receptors, which are ligand-gated chloride channels. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene have been associated with epilepsy and febrile seizures. Multiple transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008], |
