| Product name: |
GALR1 rabbit pAb |
| Reactivity: |
Human;Mouse |
| Alternative Names: |
GALR1; GALNR; GALNR1; Galanin receptor type 1; GAL1-R; GALR-1 |
| Source: |
Rabbit |
| Dilutions: |
Immunofluorescence: 1/200 – 1/1000. ELISA: 1/5000. Not yet tested in other applications. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from human GALR1. AA range:161-210 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Molecular Weight: |
39kD |
| GeneID: |
2587 |
| Human Swiss-Prot No: |
P47211 |
| Cellular localization: |
Cell membrane; Multi-pass membrane protein. |
| Background: |
The neuropeptide galanin elicits a range of biological effects by interaction with specific G-protein-coupled receptors. Galanin receptors are seven-transmembrane proteins shown to activate a variety of intracellular second-messenger pathways. GALR1 inhibits adenylyl cyclase via a G protein of the Gi/Go family. GALR1 is widely expressed in the brain and spinal cord, as well as in peripheral sites such as the small intestine and heart. [provided by RefSeq, Jul 2008], |
