| Product name: |
GPR172A rabbit pAb |
| Reactivity: |
Human;Rat;Mouse; |
| Alternative Names: |
SLC52A2; GPR172A; PAR1; RFT3; Solute carrier family 52; riboflavin transporter, member 2; Porcine endogenous retrovirus A receptor 1; PERV-A receptor 1; Protein GPR172A; Riboflavin transporter 3; hRFT3 |
| Source: |
Rabbit |
| Dilutions: |
Western Blot: 1/500 – 1/2000. Immunofluorescence: 1/200 – 1/1000. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from human PEVR1. AA range:43-92 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
46kD |
| GeneID: |
79581 |
| Human Swiss-Prot No: |
Q9HAB3 |
| Cellular localization: |
Cell membrane ; Multi-pass membrane protein . |
| Background: |
This gene encodes a membrane protein which belongs to the riboflavin transporter family. In humans, riboflavin must be obtained by intestinal absorption because it cannot be synthesized by the body. The water-soluble vitamin riboflavin is processed to the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD) which then act as intermediaries in many cellular metabolic reactions. Paralogous members of the riboflavin transporter gene family are located on chromosomes 17 and 20. Unlike other members of this family, this gene has higher expression in brain tissue than small intestine. Alternative splicing of this gene results in multiple transcript variants encoding the same protein. Mutations in this gene have been associated with Brown-Vialetto-Van Laere syndrome 2 – an autosomal recessive progressive neurologic disorder characterized by deafness, bulbar dysfunctio |
