HIF-3α rabbit pAb – TO7165
TO7165
Size:Price:
50 µL$148.00
100 µL$248.00

Overview

Product name: HIF-3 rabbit pAb
Reactivity: Human;Mouse;Rat
Alternative Names: Hypoxia-inducible factor 3-alpha; HIF-3-alpha; HIF3-alpha; Basic-helix-loop-helix-PAS protein MOP7; Class E basic helix-loop-helix protein 17; bHLHe17; HIF3-alpha-1; Inhibitory PAS domain protein; IPAS; Member of PAS protein 7; PAS domain-c
Source: Rabbit
Dilutions: Western Blot: 1/500 – 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human HIF-3alpha. AA range:305-354
Storage: -20C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 72kD
GeneID: 64344
Human Swiss-Prot No: Q66K72
Cellular localization: nucleus,nucleoplasm,mitochondrion,cytosol,nuclear speck,
Background: hypoxia inducible factor 3 alpha subunit(HIF3A) Homo sapiens The protein encoded by this gene is the alpha-3 subunit of one of several alpha/beta-subunit heterodimeric transcription factors that regulate many adaptive responses to low oxygen tension (hypoxia). The alpha-3 subunit lacks the transactivation domain found in factors containing either the alpha-1 or alpha-2 subunits. It is thought that factors containing the alpha-3 subunit are negative regulators of hypoxia-inducible gene expression. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2011],