| Product name: |
HP-1α (5E3) Mouse mAb |
| Reactivity: |
Human, Mouse, Rat |
| Alternative Names: |
Antigen p25, CBX5, HEL25, Heterochromatin protein 1 |
| Source: |
Mouse |
| Dilutions: |
WB 1:500-1,000 IHC 1:100-200 |
| Immunogen: |
Recombinant Protein |
| Storage: |
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Clonality: |
Monoclonal |
| Isotype: |
IgG1 |
| Concentration: |
1mg/mL |
| Observed Band: |
22kDa |
| GeneID: |
23468 |
| Human Swiss-Prot No: |
P45973 |
| Cellular localization: |
Cytoplasm, Membrane, Nucleus |
| Background: |
Heterochromatin protein 1 (HP1) is a family of heterochromatic adaptor molecules involved in both gene silencing and higher order chromatin structure. All three HP1 family members (α, β, and γ) are primarily associated with centromeric heterochromatin. |