| Product name: |
I17RD rabbit pAb |
| Reactivity: |
Human;Mouse |
| Source: |
Rabbit |
| Dilutions: |
WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen: |
Synthesized peptide derived from part region of human protein |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
81kD |
| GeneID: |
54756 |
| Human Swiss-Prot No: |
Q8NFM7 |
| Cellular localization: |
Golgi apparatus membrane ; Single-pass type I membrane protein . Cell membrane ; Single-pass type I membrane protein . Predominantly associated with the Golgi apparatus and is partially translocated to the plasma membrane upon stimulation.; [Isoform 4]: Cytoplasm. |
| Background: |
This gene encodes a membrane protein belonging to the interleukin-17 receptor (IL-17R) protein family. The encoded protein is a component of the interleukin-17 receptor signaling complex, and the interaction between this protein and IL-17R does not require the interleukin. The gene product also affects fibroblast growth factor signaling, inhibiting or stimulating growth through MAPK/ERK signaling. Alternate splicing generates multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jan 2016], |
