| Product name: |
IL-20 rabbit pAb |
| Reactivity: |
Human;Mouse |
| Alternative Names: |
IL20; ZCYTO10; Interleukin-20; IL-20; Cytokine Zcyto10 |
| Source: |
Rabbit |
| Dilutions: |
Western Blot: 1/500 – 1/2000. ELISA: 1/5000. Not yet tested in other applications. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from human IL-20. AA range:12-61 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
28kD |
| GeneID: |
50604 |
| Human Swiss-Prot No: |
Q9NYY1 |
| Cellular localization: |
Secreted. |
| Background: |
The protein encoded by this gene is a cytokine structurally related to interleukin 10 (IL10). This cytokine has been shown to transduce its signal through signal transducer and activator of transcription 3 (STAT3) in keratinocytes. A specific receptor for this cytokine is found to be expressed in skin and upregulated dramatically in psoriatic skin, suggesting a role for this protein in epidermal function and psoriasis. [provided by RefSeq, Jul 2008], |
