| Product name: |
INT7 rabbit pAb |
| Reactivity: |
Human; Mouse |
| Alternative Names: |
Integrator complex subunit 7 (Int7) |
| Source: |
Rabbit |
| Dilutions: |
WB 1:500-2000 |
| Immunogen: |
Synthesized peptide derived from human INT7 AA range: 364-414 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
105kD |
| GeneID: |
25896 |
| Human Swiss-Prot No: |
Q9NVH2 |
| Cellular localization: |
Nucleus . Chromosome . Cytoplasm . Localizes to sites of DNA damage in a H2AX-independent manner. |
| Background: |
This gene encodes a subunit of the integrator complex. The integrator complex associates with the C-terminal domain of RNA polymerase II and mediates 3′-end processing of the small nuclear RNAs U1 and U2. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010], |