| Product name: |
Integrin 3 (phospho Tyr785) rabbit pAb |
| Reactivity: |
Human;Mouse;Rat |
| Alternative Names: |
ITGB3; GP3A; Integrin beta-3; Platelet membrane glycoprotein IIIa; GPIIIa; CD antigen CD61 |
| Source: |
Rabbit |
| Dilutions: |
IF/ICC 1:50-300; ELISA 1:2000-20000; IHC-p 1:50-200 |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from human Integrin beta3 around the phosphorylation site of Tyr785. AA range:739-788 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
87kD |
| GeneID: |
3690 |
| Human Swiss-Prot No: |
P05106 |
| Cellular localization: |
Cell membrane ; Single-pass type I membrane protein . Cell projection, lamellipodium membrane . Cell junction, focal adhesion . Cell junction, synapse, postsynaptic cell membrane ; Single-pass type I membrane protein . Cell junction, synapse . |
| Background: |
The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. [provided by RefSeq, Jul 2008], |
