| Product name: |
Jagged1 rabbit pAb |
| Reactivity: |
Human;Mouse;Rat |
| Alternative Names: |
JAG1; JAGL1; Protein jagged-1; Jagged1; hJ1; CD339 |
| Source: |
Rabbit |
| Dilutions: |
IF: 1:50-200 Western Blot: 1/500 – 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from the Internal region of human JAG1. AA range:981-1030 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
140kD |
| GeneID: |
182 |
| Human Swiss-Prot No: |
P78504 |
| Cellular localization: |
Membrane; Single-pass type I membrane protein. |
| Background: |
The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis. [provided by RefSeq, Jul 2008], |
