| Product name: |
KBTBA rabbit pAb |
| Reactivity: |
Human;Rat |
| Source: |
Rabbit |
| Dilutions: |
WB 1:500-2000;IHC-p 1:50-300 |
| Immunogen: |
Synthesized peptide derived from human KBTBA AA range: 268-318 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Molecular Weight: |
67kD |
| GeneID: |
10324 |
| Human Swiss-Prot No: |
O60662 |
| Cellular localization: |
Cytoplasm . Cytoplasm, cytoskeleton . Cell projection, pseudopodium . Cell projection, ruffle . Cytoplasm, myofibril, sarcomere, M line . Sarcoplasmic reticulum membrane . Endoplasmic reticulum membrane . Predominantly cytoplasmic but can colocalize with F-actin at the membrane ruffle-like structures at the tips of transformation-specific pseudopodia. . |
| Background: |
This gene is a member of the kelch-like family. The encoded protein contains a BACK domain, a BTB/POZ domain, and 5 Kelch repeats. This protein is thought to function in skeletal muscle development and maintenance. Mutations in this gene have been associated with nemaline myopathy (NM), a rare congenital muscle disorder. [provided by RefSeq, Mar 2015], |
