| Product name: |
KiSS-1R rabbit pAb |
| Reactivity: |
Human;Rat;Mouse; |
| Alternative Names: |
KISS1R; AXOR12; GPR54; KiSS-1 receptor; KiSS-1R; G-protein coupled receptor 54; G-protein coupled receptor OT7T175; hOT7T175; Hypogonadotropin-1; Kisspeptins receptor; Metastin receptor |
| Source: |
Rabbit |
| Dilutions: |
Immunohistochemistry: 1/100 – 1/300, Immunofluorescence: 1/100 – 1/500. ELISA: 1/5000. Not yet tested in other applications. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from human KISS1R. AA range:301-350 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Molecular Weight: |
43kD |
| GeneID: |
84634 |
| Human Swiss-Prot No: |
Q969F8 |
| Cellular localization: |
Cell membrane; Multi-pass membrane protein. |
| Background: |
The protein encoded by this gene is a galanin-like G protein-coupled receptor that binds metastin, a peptide encoded by the metastasis suppressor gene KISS1. The tissue distribution of the expressed gene suggests that it is involved in the regulation of endocrine function, and this is supported by the finding that this gene appears to play a role in the onset of puberty. Mutations in this gene have been associated with hypogonadotropic hypogonadism and central precocious puberty. [provided by RefSeq, Jul 2008], |
