The antiserum was produced against synthesized peptide derived from human ARHGEF12. AA range:449-498
Storage:
-20C/1 year
Clonality:
Polyclonal
Isotype:
IgG
Concentration:
1 mg/ml
Observed Band:
173kD
GeneID:
23365
Human Swiss-Prot No:
Q9NZN5
Cellular localization:
Cytoplasm . Membrane . Translocated to the membrane upon stimulation. .
Background:
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli working through G protein-coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein has been observed to form a myeloid/lymphoid fusion partner in acute myeloid leukemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014],