| Product name: |
LPP3 rabbit pAb |
| Reactivity: |
Human; Mouse;Rat |
| Source: |
Rabbit |
| Dilutions: |
WB 1:500-2000 |
| Immunogen: |
Synthesized peptide derived from human LPP3 AA range: 205-255 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Molecular Weight: |
34kD |
| GeneID: |
8613 |
| Human Swiss-Prot No: |
O14495 |
| Cellular localization: |
Cell membrane ; Multi-pass membrane protein . Basolateral cell membrane ; Multi-pass membrane protein . Endoplasmic reticulum membrane ; Multi-pass membrane protein . Endoplasmic reticulum-Golgi intermediate compartment membrane ; Multi-pass membrane protein . Golgi apparatus membrane ; Multi-pass membrane protein . Golgi apparatus, trans-Golgi network membrane ; Multi-pass membrane protein . Membrane raft ; Multi-pass membrane protein . Cycles between the endoplasmic reticulum and the Golgi. . |
| Background: |
The protein encoded by this gene is a member of the phosphatidic acid phosphatase (PAP) family. PAPs convert phosphatidic acid to diacylglycerol, and function in de novo synthesis of glycerolipids as well as in receptor-activated signal transduction mediated by phospholipase D. This protein is a membrane glycoprotein localized at the cell plasma membrane. It has been shown to actively hydrolyze extracellular lysophosphatidic acid and short-chain phosphatidic acid. The expression of this gene is found to be enhanced by epidermal growth factor in Hela cells. [provided by RefSeq, Mar 2010], |
