| Product name: |
MAD2L1BP rabbit pAb |
| Reactivity: |
Human;Rat;Mouse; |
| Alternative Names: |
MAD2L1BP; CMT2; KIAA0110; MAD2L1-binding protein; Caught by MAD2 protein |
| Source: |
Rabbit |
| Dilutions: |
Western Blot: 1/500 – 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen: |
Synthesized peptide derived from MAD2L1BP . at AA range: 10-90 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
31kD |
| GeneID: |
9587 |
| Human Swiss-Prot No: |
Q15013 |
| Cellular localization: |
Nucleus. Cytoplasm, cytoskeleton, spindle. During early mitosis, unevenly distributed throughout the nucleoplasm. From metaphase to anaphase, concentrated on the spindle. |
| Background: |
The protein encoded by this gene was identified as a binding protein of the MAD2 mitotic arrest deficient-like 1 (MAD2/MAD2L1). MAD2 is a key component of the spindle checkpoint that delays the onset of anaphase until all the kinetochores are attached to the spindle. This protein may interact with the spindle checkpoint and coordinate cell cycle events in late mitosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008], |
