MAF1; Repressor of RNA polymerase III transcription MAF1 homolog
Source:
Rabbit
Dilutions:
Immunohistochemistry: 1/100 – 1/300. ELISA: 1/20000. Not yet tested in other applications.
Immunogen:
Synthesized peptide derived from Maf1 . at AA range: 110-190
Storage:
-20C/1 year
Clonality:
Polyclonal
Isotype:
IgG
Concentration:
1 mg/ml
Molecular Weight:
29kD
GeneID:
84232
Human Swiss-Prot No:
Q9H063
Cellular localization:
Nucleus . Cytoplasm .
Background:
This gene encodes a protein that is similar to Maf1, a Saccharomyces cerevisiae protein highly conserved in eukaryotic cells. Yeast Maf1 is a negative effector of RNA polymerase III (Pol III). It responds to changes in the cellular environment and represses pol III transcription. Biochemical studies identified the initiation factor TFIIIB as a target for Maf1-dependent repression. [provided by RefSeq, Jul 2008],
