| Product name: |
MEK1 Rabbit pAb |
| Reactivity: |
Human, Rat, Mouse |
| Alternative Names: |
ERK activator kinase 1 antibody, MAPK kinase kinase 1 antibody, MEKK1 antibody, MKK1 antibody, PRKMK 1 antibody |
| Source: |
Rabbit |
| Dilutions: |
WB 1:1,000-2,000 IHC 1:100-200 |
| Immunogen: |
Recombinant Protein |
| Storage: |
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20C. Avoidrepeatedfreeze-thawcycles. |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1mg/mL |
| Observed Band: |
45kDa |
| GeneID: |
5604 |
| Human Swiss-Prot No: |
Q02750 |
| Background: |
MEK1 and MEK2, also called MAPK or Erk kinases, are dual-specificity protein kinases that function in a mitogen activated protein kinase cascade controlling cell growth and differentiation. Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. Activates ERK1 and ERK2 MAP kinases. |
