| Product name: |
MER/TYRO3 (Phospho-Tyr753/Tyr685) rabbit pAb |
| Reactivity: |
Human;Mouse;Rat |
| Alternative Names: |
MERTK MER |
| Source: |
Rabbit |
| Dilutions: |
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000 |
| Immunogen: |
Synthesized phospho-peptide around the phosphorylation site of human MER/TYRO3 (Phospho-Tyr753/Tyr685) |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
110kD |
| GeneID: |
10461/7301 |
| Human Swiss-Prot No: |
Q12866/Q06418 |
| Cellular localization: |
Cell membrane ; Single-pass type I membrane protein . |
| Background: |
This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP). [provided by RefSeq, Jul 2008], |
