Microcephalin rabbit pAb – TO7588
TO7588
Size:Price:
50 µL$148.00
100 µL$248.00

Overview

Product name: Microcephalin rabbit pAb
Reactivity: Human;Mouse
Alternative Names: MCPH1; Microcephalin
Source: Rabbit
Dilutions: Western Blot: 1/500 – 1/2000. Immunohistochemistry: 1/100 – 1/300. ELISA: 1/40000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human MCPH1. AA range:91-140
Storage: -20C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 93kD
GeneID: 79648
Human Swiss-Prot No: Q8NEM0
Cellular localization: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome .
Background: This gene encodes a DNA damage response protein. The encoded protein may play a role in G2/M checkpoint arrest via maintenance of inhibitory phosphorylation of cyclin-dependent kinase 1. Mutations in this gene have been associated with primary autosomal recessive microcephaly 1 and premature chromosome condensation syndrome. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2010],