| Product name: |
MPP2 rabbit pAb |
| Reactivity: |
Human; Mouse |
| Source: |
Rabbit |
| Dilutions: |
WB 1:500-2000;IHC-p 1:50-300 |
| Immunogen: |
Synthesized peptide derived from human MPP2 AA range: 439-489 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Molecular Weight: |
63kD |
| GeneID: |
4355 |
| Human Swiss-Prot No: |
Q14168 |
| Cellular localization: |
Cytoplasm, cytoskeleton . Membrane . Cell projection, dendrite . Cell junction, synapse, postsynaptic density . Prominently expressed in the postsynaptic densities of dendritic spines, is also detected in dendritic shafts. . |
| Background: |
Palmitoylated membrane protein 2 is a member of a family of membrane-associated proteins termed MAGUKs (membrane-associated guanylate kinase homologs). MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intracellular junctions. Palmitoylated membrane protein 2 contains a conserved sequence, called the SH3 (src homology 3) motif, found in several other proteins that associate with the cytoskeleton and are suspected to play important roles in signal transduction. [provided by RefSeq, Jul 2008], |
