| Product name: |
mTERF rabbit pAb |
| Reactivity: |
Human;Rat;Mouse; |
| Alternative Names: |
MTERF; Transcription termination factor; mitochondrial; Mitochondrial transcription termination factor 1; mTERF |
| Source: |
Rabbit |
| Dilutions: |
Western Blot: 1/500 – 1/2000. Immunohistochemistry: 1/100 – 1/300. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from human MTERF. AA range:267-316 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
46kD |
| GeneID: |
7978 |
| Human Swiss-Prot No: |
Q99551 |
| Cellular localization: |
Mitochondrion. |
| Background: |
This gene encodes a mitochondrial transcription termination factor. This protein participates in attenuating transcription from the mitochondrial genome; this attenuation allows higher levels of expression of 16S ribosomal RNA relative to the tRNA gene downstream. The product of this gene has three leucine zipper motifs bracketed by two basic domains that are all required for DNA binding. There is evidence that, for this protein, the zippers participate in intramolecular interactions that establish the three-dimensional structure required for DNA binding. [provided by RefSeq, Jul 2008], |
