| Product name: |
mtTFA rabbit pAb |
| Reactivity: |
Human;Rat;Mouse;;Bovine |
| Alternative Names: |
TFAM; TCF6; TCF6L2; Transcription factor A; mitochondrial; mtTFA; Mitochondrial transcription factor 1; MtTF1; Transcription factor 6; TCF-6; Transcription factor 6-like 2 |
| Source: |
Rabbit |
| Dilutions: |
WB 1:500-2000;Immunohistochemistry: 1/100 – 1/300. Immunofluorescence: 1/200 – 1/1000. ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from human TFAM. AA range:131-180 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
22kd |
| GeneID: |
7019 |
| Human Swiss-Prot No: |
Q00059 |
| Cellular localization: |
Mitochondrion . Mitochondrion matrix, mitochondrion nucleoid . |
| Background: |
This gene encodes a key mitochondrial transcription factor containing two high mobility group motifs. The encoded protein also functions in mitochondrial DNA replication and repair. Sequence polymorphisms in this gene are associated with Alzheimer’s and Parkinson’s diseases. There are pseudogenes for this gene on chromosomes 6, 7, and 11. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012], |
