| Product name: |
MYL2 rabbit pAb |
| Reactivity: |
Human;Mouse;Rat |
| Alternative Names: |
Myosin regulatory light chain 2, ventricular/cardiac muscle isoform (MLC-2) (MLC-2v) |
| Source: |
Rabbit |
| Dilutions: |
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000 |
| Immunogen: |
Synthesized peptide derived from human MYL2. at AA range: 91-140 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
18kD |
| GeneID: |
4633 |
| Human Swiss-Prot No: |
P10916 |
| Cellular localization: |
Cytoplasm, myofibril, sarcomere, A band . |
| Background: |
Thus gene encodes the regulatory light chain associated with cardiac myosin beta (or slow) heavy chain. Ca+ triggers the phosphorylation of regulatory light chain that in turn triggers contraction. Mutations in this gene are associated with mid-left ventricular chamber type hypertrophic cardiomyopathy. [provided by RefSeq, Jul 2008], |
