| Cellular localization: |
[Isoform 1]: Cytoplasm . Nucleus . Colocalizes with RNA polymerase II. Absent from nucleoli and does not colocalize with RNA polymerase I. Translocates to nuclear speckles upon exposure to inhibitors of RNA polymerase II transcription.; [Isoform 2]: Cytoplasm. Cell membrane ; Peripheral membrane protein ; Cytoplasmic side . Cell projection, stereocilium membrane . Cell projection, ruffle . Cytoplasmic vesicle . Colocalizes with CABP1 and CIB1 at cell margin, membrane ruffles and punctate regions on the cell membrane. Colocalizes in adipocytes with GLUT4 at actin-based membranes. Colocalizes with GLUT4 at insulin-induced ruffles at the cell membrane. Localizes transiently at cell membrane to region known to be enriched in PIP2. Activation of phospholipase C results in its redistribution to |
