| Product name: |
Myosin Id rabbit pAb |
| Reactivity: |
Human;Mouse;Rat |
| Alternative Names: |
MYO1D; KIAA0727; Unconventional myosin-Id |
| Source: |
Rabbit |
| Dilutions: |
Immunohistochemistry: 1/100 – 1/300. ELISA: 1/40000. Not yet tested in other applications. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from human MYO1D. AA range:825-874 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Molecular Weight: |
116kD |
| GeneID: |
4642 |
| Human Swiss-Prot No: |
O94832 |
| Cellular localization: |
Cytoplasm . Perikaryon . Cell projection, dendrite . Early endosome . Cytoplasm, cell cortex . Colocalizes with the actin cytoskeleton in the cell cortex close to the apical cell membrane. Colocalizes with cytoplasmic puncta that are reminiscent of transport vesicles. . |
| Background: |
function:Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments.,similarity:Contains 1 myosin head-like domain.,similarity:Contains 2 IQ domains.,subunit:Binds calmodulin through its IQ motifs.,tissue specificity:Expressed in many tissues. Highest levels in brain, followed by lung and ovary; expression is lowest in spleen., |
