| Background: |
caution:Although related to the peptidase M28 family, it is probably inactive as an hydrolase due to lack of the conserved zinc-binding and active sites.,function:May be catalytically inactive.,miscellaneous:The gene maps to 3q26.31, a region associated with Cornelia de Lange syndrome. However, PubMed:15168106 failed to identify specific mutations in a panel of DNA samples from patients with Cornelia de Lange syndrome.,sequence caution:Contaminating sequence at the C-terminus.,similarity:Belongs to the peptidase M28 family. M28B subfamily.,tissue specificity:Expressed at higher level in kidney and placenta. In embryo, it is mainly confined to duodenal and stomach endoderm, mesonephros, metanephros and pancreas., |
