Nicalin rabbit pAb – TO6862
TO6862
Size:Price:
50 µL$148.00
100 µL$248.00

Overview

Product name: Nicalin rabbit pAb
Reactivity: Human;Mouse;Rat
Alternative Names: NCLN; Nicalin; Nicastrin-like protein
Source: Rabbit
Dilutions: Western Blot: 1/500 – 1/2000. Immunohistochemistry: 1/100 – 1/300. ELISA: 1/40000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human NCLN. AA range:474-523
Storage: -20C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 63kD
GeneID: 56926
Human Swiss-Prot No: Q969V3
Cellular localization: Endoplasmic reticulum membrane ; Single-pass membrane protein .
Background: function:May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning.,similarity:Belongs to the nicastrin family.,subunit:Interacts with NOMO2. Due to the strong similarity between NOMO1, NOMO2 and NOMO3, it probably also interacts with NOMO1 and NOMO3. Participates in a large protein complex, which is not related to the gamma-secretase complex.,tissue specificity:Highly expressed in pancreas and skeletal muscle and, at lower levels, in heart.,