| Product name: |
NOP56 rabbit pAb |
| Reactivity: |
Human;Mouse;Rat |
| Alternative Names: |
Nucleolar protein 56 (Nucleolar protein 5A) |
| Source: |
Rabbit |
| Dilutions: |
Western Blot: 1/500 – 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen: |
Synthesized peptide derived from NOP56 at AA range: 191-240 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
65kD |
| GeneID: |
10528 |
| Human Swiss-Prot No: |
O00567 |
| Cellular localization: |
Nucleus, nucleolus . Cytoplasm . Nucleus, nucleoplasm . |
| Background: |
Nop56p is a yeast nucleolar protein that is part of a complex with the nucleolar proteins Nop58p and fibrillarin. Nop56p is required for assembly of the 60S ribosomal subunit and is involved in pre-rRNA processing. The protein encoded by this gene is similar in sequence to Nop56p and is also found in the nucleolus. Expansion of a GGCCTG repeat from 3-8 copies to 1500-2500 copies in an intron of this gene results in spinocerebellar ataxia 36. Multiple transcript variants encoding several different isoforms have been found for this gene, but the full-length nature of most of them has not been determined. [provided by RefSeq, Jul 2016], |
