| Product name: |
NRG4 rabbit pAb |
| Reactivity: |
Human;Mouse |
| Source: |
Rabbit |
| Dilutions: |
WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen: |
Synthesized peptide derived from human protein . at AA range: 11-60 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
12kD |
| GeneID: |
145957 |
| Human Swiss-Prot No: |
Q8WWG1 |
| Cellular localization: |
[Pro-neuregulin-4, membrane-bound isoform]: Cell membrane ; Single-pass type I membrane protein . Does not seem to be active. .; [Neuregulin-4]: Secreted . |
| Background: |
The neuregulins, including NRG4, activate type-1 growth factor receptors (see EGFR; MIM 131550) to initiating cell-to-cell signaling through tyrosine phosphorylation (Harari et al., 1999 [PubMed 10348342]).[supplied by OMIM, Mar 2008], |