| Product name: |
P53 Rabbit pAb |
| Reactivity: |
Rat, Mouse |
| Alternative Names: |
Cellular tumor antigen p53 antibody, Cys 51 stop antibody, Tp53 antibody, Tumor protein p53 antibody |
| Source: |
Rabbit |
| Dilutions: |
WB 1:1,000-2,000 IHC 1:500-1,000 |
| Immunogen: |
Synthetic Peptide |
| Storage: |
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20C. Avoidrepeatedfreeze-thawcycles. |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1mg/mL |
| Observed Band: |
53kDa |
| GeneID: |
7157 |
| Human Swiss-Prot No: |
P04637 |
| Cellular localization: |
Cytoplasm, Cytoplasm, Nucleus |
| Background: |
p53 plays a major role in the cellular response to DNA damage and other genomic aberrations. The activation of p53 can lead to either cell cycle arrest and DNA repair, or apoptosis. p53 is phosphorylated at multiple sites in vivo and by several different protein kinases in vitro. |
