| Product name: |
PAR-3 rabbit pAb |
| Reactivity: |
Human;Rat;Mouse; |
| Alternative Names: |
F2RL2; PAR3; Proteinase-activated receptor 3; PAR-3; Coagulation factor II receptor-like 2; Thrombin receptor-like 2 |
| Source: |
Rabbit |
| Dilutions: |
Immunofluorescence: 1/200 – 1/1000. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from human F2RL2. AA range:38-87 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Molecular Weight: |
43kD |
| GeneID: |
2151 |
| Human Swiss-Prot No: |
O00254 |
| Cellular localization: |
Cell membrane; Multi-pass membrane protein. |
| Background: |
This gene encodes a member of the protease-activated receptor (PAR) family which is a subfamily of the seven transmembrane G protein-coupled cell surface receptor family. The encoded protein acts as a cofactor in the thrombin-mediated cleavage and activation of the protease-activated receptor family member PAR4. The encoded protein plays an essential role in hemostasis and thrombosis. Alternate splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Feb 2012], |
