| Product name: |
PDE6G Polyclona Antibody |
| Reactivity: |
Human; Mouse |
| Alternative Names: |
Retinal rod rhodopsin-sensitive cGMP 3′,5′-cyclic phosphodiesterase subunit gamma (GMP-PDE gamma;EC 3.1.4.35) |
| Source: |
Rabbit |
| Dilutions: |
IHC-p 1:50-200, ELISA(peptide)1:5000-20000 |
| Immunogen: |
Synthesized peptide derived from human PDE6G AA range: 10-90 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| GeneID: |
5148 |
| Human Swiss-Prot No: |
P18545 |
| Cellular localization: |
plasma membrane,photoreceptor disc membrane, |
| Background: |
This gene encodes the gamma subunit of cyclic GMP-phosphodiesterase, which is composed of alpha- and beta- catalytic subunits and two identical, inhibitory gamma subunits. This gene is expressed in rod photoreceptors and functions in the phototransduction signaling cascade. It is also expressed in a variety of other tissues, and has been shown to regulate the c-Src protein kinase and G-protein-coupled receptor kinase 2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2009], |
