| Product name: |
PDLIM5 (phospho Tyr251) rabbit pAb |
| Reactivity: |
Human;Rat;Mouse; |
| Alternative Names: |
PDLIM5; ENH; L9; PDZ and LIM domain protein 5; Enigma homolog; Enigma-like PDZ and LIM domains protein |
| Source: |
Rabbit |
| Dilutions: |
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000 |
| Immunogen: |
Synthesized phospho-peptide around the phosphorylation site of human PDLIM5 (phospho Tyr251) |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
64kD |
| GeneID: |
10611 |
| Human Swiss-Prot No: |
Q96HC4 |
| Cellular localization: |
Cell junction, synapse, postsynaptic density . Cell junction, synapse, presynapse . Cell junction, synapse, postsynapse . Cytoplasm, cytosol . Detected both at presynaptic and postsynaptic sites, exclusively at excitatory synapses, but not inhibitory synapses, in hippocampal neurons. . |
| Background: |
This gene encodes a member of a family of proteins that possess a 100-amino acid PDZ domain at the N terminus and one to three LIM domains at the C-terminus. This family member functions as a scaffold protein that tethers protein kinases to the Z-disk in striated muscles. It is thought to function in cardiomyocyte expansion and in restraining postsynaptic growth of excitatory synapses. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2012], |
