| Product name: |
PDZK3 rabbit pAb |
| Reactivity: |
Human;Mouse;Rat |
| Alternative Names: |
PDZD2; AIPC; KIAA0300; PDZK3; PDZ domain-containing protein 2; Activated in prostate cancer protein; PDZ domain-containing protein 3 |
| Source: |
Rabbit |
| Dilutions: |
Immunohistochemistry: 1/100 – 1/300. Immunofluorescence: 1/200 – 1/1000. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from human PDZD2. AA range:51-100 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Molecular Weight: |
302kD |
| GeneID: |
23037 |
| Human Swiss-Prot No: |
O15018 |
| Cellular localization: |
Nucleus . Cytoplasm . Endoplasmic reticulum . At cell-cell contacts in lung epithelial cells. .; [Processed PDZ domain-containing protein 2]: Secreted . |
| Background: |
The protein encoded by this gene contains six PDZ domains and shares sequence similarity with pro-interleukin-16 (pro-IL-16). Like pro-IL-16, the encoded protein localizes to the endoplasmic reticulum and is thought to be cleaved by a caspase to produce a secreted peptide containing two PDZ domains. In addition, this gene is upregulated in primary prostate tumors and may be involved in the early stages of prostate tumorigenesis. [provided by RefSeq, Dec 2015], |
