| Product name: |
PERM (light chain, Cleaved-Gly278) rabbit pAb |
| Reactivity: |
Human;Rat;Mouse; |
| Alternative Names: |
Myeloperoxidase (MPO;EC 1.11.2.2) [Cleaved into: Myeloperoxidase; 89 kDa myeloperoxidase; 84 kDa myeloperoxidase; Myeloperoxidase light chain; Myeloperoxidase heavy chain] |
| Source: |
Rabbit |
| Dilutions: |
WB 1:500-2000;IHC-p 1:50-300 |
| Immunogen: |
Synthesized peptide derived from human PERM (light chain, Cleaved-Gly278) |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
12 84 89kD |
| GeneID: |
4353 |
| Human Swiss-Prot No: |
P05164 |
| Cellular localization: |
Lysosome. |
| Background: |
Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of neutrophils. [provided by RefSeq, Nov 2014], |
