| Product name: |
PRIM1 rabbit pAb |
| Reactivity: |
Human;Mouse;Rat |
| Alternative Names: |
PRIM1; DNA primase small subunit; DNA primase 49 kDa subunit; p49 |
| Source: |
Rabbit |
| Dilutions: |
Western Blot: 1/500 – 1/2000. Immunohistochemistry: 1/100 – 1/300. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from human PRIM1. AA range:371-420 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
50kD |
| GeneID: |
5557 |
| Human Swiss-Prot No: |
P49642 |
| Cellular localization: |
nucleoplasm,alpha DNA polymerase:primase complex,membrane,primosome complex, |
| Background: |
The replication of DNA in eukaryotic cells is carried out by a complex chromosomal replication apparatus, in which DNA polymerase alpha and primase are two key enzymatic components. Primase, which is a heterodimer of a small subunit and a large subunit, synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication. The protein encoded by this gene is the small, 49 kDa primase subunit. [provided by RefSeq, Jul 2008], |
