PROZ rabbit pAb – TO20310
TO20310
Size:Price:
50 µL$148.00
100 µL$248.00
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Overview

Product name: PROZ rabbit pAb
Reactivity: Human;Rat;Mouse;
Alternative Names: Vitamin K-dependent protein Z
Source: Rabbit
Dilutions: WB 1:500-2000;IHC-p 1:50-300
Immunogen: Synthesized peptide derived from human PROZ AA range: 141-190
Storage: -20C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Molecular Weight: 44kD
GeneID: 8858
Human Swiss-Prot No: P22891
Cellular localization: Secreted.
Background: This gene encodes a liver vitamin K-dependent glycoprotein that is synthesized in the liver and secreted into the plasma. The encoded protein plays a role in regulating blood coagulation by complexing with protein Z-dependent protease inhibitor to directly inhibit activated factor X at the phospholipid surface. Deficiencies in this protein are associated with an increased risk of ischemic arterial diseases and fetal loss. Mutations in this gene are the cause of protein Z deficiency. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012],