| Product name: |
PRPF18 rabbit pAb |
| Reactivity: |
Human;Mouse;Rat |
| Alternative Names: |
PRPF18; HPRP18; Pre-mRNA-splicing factor 18; PRP18 homolog; hPRP18 |
| Source: |
Rabbit |
| Dilutions: |
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000 |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from human PRPF18. AA range:182-231 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
40kD |
| GeneID: |
8559 |
| Human Swiss-Prot No: |
Q99633 |
| Cellular localization: |
Nucleus speckle . Colocalizes with spliceosomal snRNPs. . |
| Background: |
Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is found to be essential for the catalytic step II in pre-mRNA splicing process. It is found in the spliceosome, and contains seven WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to the yeast splicing factor Prp18. [provided by RefSeq, Jul 2008], |
