| Product name: |
RECK rabbit pAb |
| Reactivity: |
Human;Mouse |
| Alternative Names: |
RECK; ST15; Reversion-inducing cysteine-rich protein with Kazal motifs; hRECK; Suppressor of tumorigenicity 15 protein |
| Source: |
Rabbit |
| Dilutions: |
WB 1:500-2000 Immunohistochemistry: 1/100 – 1/300. Immunofluorescence: 1/200 – 1/1000. ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from human RECK. AA range:21-70 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
110kD |
| GeneID: |
8434 |
| Human Swiss-Prot No: |
O95980 |
| Cellular localization: |
Cell membrane ; Lipid-anchor, GPI-anchor . |
| Background: |
The protein encoded by this gene is a cysteine-rich, extracellular protein with protease inhibitor-like domains whose expression is suppressed strongly in many tumors and cells transformed by various kinds of oncogenes. In normal cells, this membrane-anchored glycoprotein may serve as a negative regulator for matrix metalloproteinase-9, a key enzyme involved in tumor invasion and metastasis. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015], |
