| Product name: |
Recombinant Mouse/Rat TGF-beta 1 |
| Description: |
Recombinant Mouse/Rat Transforming Growth Factor Beta 1 is produced by our Mammalian expression system and the target gene encoding Ala279-Ser390 is expressed. |
| Accession: |
P04202 |
| Molecular weight: |
12.8 KDa |
| Apparent molecular weight: |
13 KDa, reducing conditions |
| Purity: |
Greater than 95% as determined by reducing SDS-PAGE. |
| Endotoxin: |
Less than 0.001 ng/g (0.01 EU/g) as determined by LAL test. |
| Biological activity: |
Immobilized Mouse/Rat TGF-beta 1(Cat#CK33) at 2g/ml (100 l/well) can bind Mouse TGFBR2-His(Cat#CM05).The ED50 of Mouse TGFBR2-His(Cat#CM05)is 2.5 ug/ml. |
| Redissolve: |
Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100g/ml. Dissolve the lyophilized protein in 4mM HCl. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Storage: |
Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
| Delivery condition: |
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below. |
| Background: |
Transforming growth factor beta 1 (TGF1) is the prototype of a growing superfamily of peptide growth factors and plays a prominent role in a variety of cellular processes, including cell-cycle progression, cell differentiation, reproductive function, development, motility, adhesion, neuronal growth, bone morphogenesis, wound healing, and immune surveillance. TGF-1, TGF-2 and TGF-3 signal via the same heteromeric receptor complex, consisting of a ligand binding TGF- receptor type II (TR-II), and a TGF- receptor type I (TR-I). Signal transduction from the receptor to the nucleus is mediated via SMADs. TGF- expression is found in cartilage, bone, teeth, muscle, heart, blood vessels, haematopoitic cells, lung, kidney, gut, liver, eye, ear, skin, and the nervous system. |
