| Product name: |
RhoGEF p115 rabbit pAb |
| Reactivity: |
Human;Mouse;Rat |
| Alternative Names: |
ARHGEF1; Rho guanine nucleotide exchange factor 1; 115 kDa guanine nucleotide exchange factor; p115-RhoGEF; p115RhoGEF; Sub1.5 |
| Source: |
Rabbit |
| Dilutions: |
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000 |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from human ARHGEF1. AA range:162-211 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
105kD |
| GeneID: |
9138 |
| Human Swiss-Prot No: |
Q92888 |
| Cellular localization: |
Cytoplasm . Membrane . Translocated to the membrane by activated GNA13 or LPA stimulation. |
| Background: |
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate Rho-dependent signals. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined. [provided by RefSeq, Jul 2008], |