| Product name: |
Ribosomal Protein LP2 rabbit pAb |
| Reactivity: |
Human;Mouse;Rat |
| Alternative Names: |
RPLP2; D11S2243E; RPP2; 60S acidic ribosomal protein P2; Renal carcinoma antigen NY-REN-44 |
| Source: |
Rabbit |
| Dilutions: |
Immunohistochemistry: 1/100 – 1/300. ELISA: 1/40000. Not yet tested in other applications. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from human RPLP2. AA range:21-70 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Molecular Weight: |
12kD |
| GeneID: |
6181 |
| Human Swiss-Prot No: |
P05387 |
| Cellular localization: |
cytosol,ribosome,focal adhesion,membrane,cytosolic large ribosomal subunit,preribosome, large subunit precursor,extracellular exosome, |
| Background: |
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal phosphoprotein that is a component of the 60S subunit. The protein, which is a functional equivalent of the E. coli L7/L12 ribosomal protein, belongs to the L12P family of ribosomal proteins. It plays an important role in the elongation step of protein synthesis. Unlike most ribosomal proteins, which are basic, the encoded protein is acidic. Its C-terminal end is nearly identical to the C-terminal ends of the ribosomal phosphoproteins P0 and P1. The P2 protein can interact with P0 and P1 to form a pentameric complex consisting of P1 and P2 dimers, and a P0 monomer. The protein is located in the cytoplasm. As is typical for genes |
